It is an overthecounter medication that is used for the relief of diarrheal syndromes, including acute, nonspecific infectious diarrhea. It does not contain all the information about your medicine that you may need to know, so please ask your doctor or pharmacist if you have any questions. Loperamide hydrochloride 4pchlorophenyl4hydroxyn,ndimethyldiphenyl1piperidine bytyramide monhydrochloride is a white powder which is slightly soluble in water, freely soluble in alcohol and in methanol. Loperamide hcl 2 mg tablet uses, dosage, side effects. Imodium loperamide hydrochloride is indicated for the control and symptomatic relief of acute nonspecific diarrhea in patients 2 years of age and older and of. Grind a number of tablets, equiva acceptance criteria. Identification product name thiamine hydrochloride uspfcc cat no. It is also used to treat longterm diarrhea associated with other diseases. Loperamide acute dosage and side effects cara care. Details of the supplier of the safety data sheet emergency telephone number. The name comes from the genus name piper, which is the latin word for pepper. Loperamide can be present in breast milk, and is not recommended for breastfeeding mothers.
Jan 01, 1990 the ultraviolet absorption spectrum of approximately 40 mg loperamide hydrochloride in 100 ml of 0. Loperamide treats only the symptoms, not the cause of the diarrhea e. Loperamide hydrochloride is an approved prescription medication. Unlike diphenoxylate or codeine, loperamide does not appear to exert opiate activity in man at normal therapeutic doses. Loperamide hydrochloride cas 34552835 calbiochem empirical formula hill notation. Dilute with mobile phase to volume, mix, and filter. Loperamide, sold under the brand name imodium, among others, is a medication used to decrease the frequency of diarrhea.
It is not recommended for those with blood in the stool, mucus in the stool, or fevers. O4700100 casno 67038 synonyms thiamine chloride hydrochloride. It is used to relieve the symptoms of diarrhea that start suddenly and lasts for a few days. Osha, cma, ansi, canadian whmis standards, european. Loperamide, a butyramide derivative is a new agent for use in symptomatic control of acute nonspecific diarrhoea and chronic diarrhoea. Loperamide hydrochloride tablets type of posting revision bulletin posting date 30sep2016 official date 01oct2016 expert committee chemical medicines monographs 3 reason for revision compliance. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed. Ep22175b1 process for the preparation of loperamide.
Simethicone is an orally administered antifoaming agent. Loperamide hydrochloride cas 34552835 calbiochem 508162. Loperamide hydrochloride 2mg tablets read this leaflet carefully before taking this medicine. Amazon basic care loperamide hydrochloride and simethicone tablets, 2 mg125 mg, antidiarrheal and antigas, 24 count 4.
Do not use if you have ever had a rash or other allergic reaction to loperamide hcl. Linearity curve for loperamide hydrochloride table1. Extreme high moderate low section 1 chemical product and company identification product name loperamide hydrochloride statement of hazardous nature considered a hazardous substance according to osha 29 cfr 1910. It is used for symptomatic treatment for adults and adolescents from the age of 12 if no causal therapy is available. A simple, selective, linear, specific, precise and accurate high performance liquid chromatography hplc method was developed and validated for rapid assay of loperamide hydrochloride in finished.
Pdf method validation for assay of loperamide hydrochloride. Dilute this 30, unless otherwise specified by the manufacturer. Safety data sheet revision date 19feb2020 revision number 2 1. This heterocyclic amine consists of a sixmembered ring containing five methylene bridges ch 2 and one amine bridge nh. When taken in large quantities, the drug can produce a euphoric high similar to opioids, causing many individuals struggling with opioid addictions to abuse loperamide either to get high or help manage withdrawal symptoms. Loperamide hcl does not cross the bloodbrain barrier. Loperamide hydrochloride contains not less than 98. Available coupons save up to 80% on your prescription with webmdrx.
Common side effects include dizziness, drowsiness, vomiting, and constipation. Loperamide hydrochloride c29h34cl2n2o2 cid 71420 structure, chemical names, physical and chemical properties, classification, patents, literature. Common side effects include abdominal pain, constipation. Loperamide imonium addiction and abuse addiction center.
Amazon basic care loperamide hydrochloride tablets, 2 mg, antidiarrheal, light green, 24 count pack of 1 4. Identification product name thiamine hydrochloride usp. Method validation for assay of loperamide hydrochloride by. Transfer a volume of oral solution, equivalent loperamide hydrochloride oral to about 1. Loperamide hydrochloride 4pchlorophenyl4hydroxyn,ndimethyl. Linearity of loperamide hydrochloride concentration, mgml area of loperamide hydrochloride peak 0. Loperamide hydrochloride oral solution 1 of 7 safety data sheet 1.
For research use only, not for human or veterinary use. Identification name loperamide accession number db00836 description. Loperamide hcl should not be used in children under 2 years loperamide hcl should not be used as the primary therapy. Dispose in accordance with local, state, and federal regulations. Loperamide hydrochloride c29h34cl2n2o2 cid 71420 structure, chemical names, physical and chemical properties, classification, patents, literature, biological. Chemicalbook provide chemical industry users with loperamide hydrochloride boiling point melting point,loperamide hydrochloride density msds formula. Articles of loperamide hydrochloride are included as well. Loperamide hydrochloride capsules loperamide hydrochloride. Piperidine is an organic compound with the molecular formula ch 2 5 nh.
Safety data sheet creation date 27jul2012 revision date 17aug2018 revision number 7 1. It is often used for this purpose in inflammatory bowel disease and short bowel syndrome. Interim revision announcement official may 1, 2014 loperamide 1. Enamines derived from piperidine are substrates in the stork enamine alkylation reaction upon treatment with calcium hypochlorite, piperidine converts to nchloropiperidine, a chloramine with the formula c 5 h 10 ncl. Loperamide hydrochloride cas 34552835 scbt santa cruz. This material is not listed on the us tsca inventory. This material is not listed on the dsl inventory but is exempt. Amazon basic care loperamide hydrochloride and simethicone tablets, 2 mg125 mg, antidiarrheal and antigas, 24 count. It is mainly used to reduce gas from the gastrointestinal tract git in patients complaining from recurrent flatulence. Anipryl selegiline hydrochloride tablets finland oel twa 5 mgm3 germany trgs 900 twas mgm3 germany trgs 900 twas 4 mgm3 selegiline hydrochloride germany dfg mak 4 mgm3 germany dfg mak ireland oel twas 6 mgm3 2. Page 27 safety data sheet according to 19072006ec, article 31 printing date 06. Ruben vardanyan, in piperidinebased drug discovery, 2017. This leaflet only applies to loperamide hydrochloride 2mg tablets. Loperamide hydrochloride 2mg tablets msds the new sds required by.
Loperamide hydrochloride is an opiate agonist with selectivity for the mor. Jan 27, 2020 to help deter misuse and abuse of otc loperamide products, fda has approved packaging changes for several tablet and capsule formulations of the drug including imodium brandname products that limit total loperamide hydrochloride content of the package to 48 mg and require use of singledose e. Vitamin b1 hydrochloride recommended use laboratory chemicals. Apr 16, 2020 loperamide hcl 2 mg tablet is a very effective antidiarrhea medication.
Controls the symptoms of diarrhea, including travelers diarrheal. Material safety data sheet of loperamide hydrochloride. Loperamide may interact with certain prescription drugs. Loperamide hydrochloride should be kept in a wellclosed container. J60168 casno 34552835 synonyms no information available recommended use laboratory chemicals. Loperamide hydrochloride safety data sheet section 2. Uses advised against food, drug, pesticide or biocidal product use details of the supplier of the safety data sheet emergency telephone number. No this sds was prepared in accordance with 29 cfr 1910. Material safety data sheet loperamide hydrochloride sc203116 hazard alert code key. Know uses, side effects, dosage, contraindications, substitutes, benefit, interactions, purpose, drug interactions. Sds of loperamide hydrochloride, safety data sheets, cas. Precautionary statements p281 use personal protective equipment as required. Dailymed medique diamode loperamide hydrochloride tablet. Loperamide hydrochloride hcl has been used in inflammatory pain experiments and to assess the functionality of proteins.
Identification product name loperamide hydrochloride cat no. Loperamide hcl systemic bioavailability is about 0. Free rx coupon save up to 80% on your prescriptions. Piperidine is a widely used to convert ketones to enamines. When using this product tiredness, drowsiness or dizziness may occur. O hcl cas number 34552835 alternate cas number not applicable molecular weight 5. Uses advised against food, drug, pesticide or biocidal. Loperamide hydrochloride tablets type of posting revision. It is a colorless liquid with an odor described as objectionable, and typical of amines. Loperamide hcl is contraindicated in patients with a known hypersensitivity to loperamide hcl or to any of the excipients.
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